I occasionally research 380 ammo to see if there have been any new developments. In general, it seems you either get under-penetration with expansion, or over-penetration without it. There are a select few brands that seem to strike a good balance. I know the famous "shooting the bull" tests determined that an XTP bullet is optimal, but I prefer to stay with big-name brands, so I'm not interested in Precision One or others. Also, if you look here:
Lucky Gunner tests more than 110 different 9mm, 45 ACP, 40 S&W and 380 ACP handgun self-defense ammunition loads in ballistic gel with analysis and video.
www.luckygunner.com
The XTP rounds didn't do so hot. They only met the 12" minimum because of failure to expand. I was reading about Federal's HST in .380, but those don't appear to do well when shot through layers of fabric. Hornady's Critical Defense seems good in the Lucky Gunner tests, but I've seen others where it doesn't fare well. I had a dud CD round at the range once, and that's shaken my confidence a bit.
So, my current carry round for Elsie is the Gold Dots. They seem to fall a hair short of the 12" mark, but they usually expand. At this point, is it really worth switching to something else? The GDs give around 11" and 0.5" expansion, which I think it fairly respectable.